https://devzone.nordicsemi.com/f/nordic-q-a/105709/device-reset-when-running-bleUsing sample Beacon and VSC with toolchain 2.4.2 and SDK 2.4.2. This runs ok on the nrf_dk(52832) but using the same hex file and loading to our own target we get this. [00:00:00.016,113] &lt;err&gt; mpsl_init: m_assert_handler: MPSL ASSERT: 112, 2134 [00en-USTelligent Community 13Wed, 15 Nov 2023 13:30:27 GMThttps://devzone.nordicsemi.com/thread/455769?ContentTypeID=1Wed, 15 Nov 2023 13:30:27 GMT137ad170-7792-4731-bb38-c0d22fbe4515:ecfb7683-b908-49a6-8d31-9150587dd4fchaakonsh<p>There&#39;s an issue with your HFXO not running when it&#39;s supposed to. See similar case:&nbsp;&nbsp;<a href="https://devzone.nordicsemi.com/f/nordic-q-a/102119/mpsl-assert-112-2134-if-using-multiple-ble-communication">MPSL ASSERT: 112, 2134 if using multiple BLE communication</a>&nbsp;&nbsp;</p> <p></p> [quote user=""]We know our board works as we have a test application that can flash LEDs and read data from SPI Flash and SPI IMU.[/quote] <p>SPI and GPIO does not typically use the HFXO, where the default HFCLK source is the internal 64MHz RC oscillator.&nbsp;</p><div style="clear:both;"></div>