https://devzone.nordicsemi.com/f/nordic-q-a/24014/differential-adc-outputHi Why does making an input differential lose a bit on the nRF52. According to the data sheet, if a channel is 10 bit and using 0.6V reference and gain 1 and input is 100mV differential, then the output will be: 0.1 * 1 / 0.6 * 512 = 85 Whereen-USTelligent Community 13Tue, 15 Aug 2017 11:46:00 GMThttps://devzone.nordicsemi.com/thread/94531?ContentTypeID=1Tue, 15 Aug 2017 11:46:00 GMT137ad170-7792-4731-bb38-c0d22fbe4515:b5b5b5dc-24b7-4cf6-8c7d-94234c47fac3run_ar<p>More details on negative values in single ended mode <a href="https://devzone.nordicsemi.com/question/70115/nrf52-saadc-noise/?answer=70166#post-id-70166">here</a>.</p><div style="clear:both;"></div>https://devzone.nordicsemi.com/thread/94530?ContentTypeID=1Thu, 03 Aug 2017 10:48:10 GMT137ad170-7792-4731-bb38-c0d22fbe4515:6294e018-7441-4dc7-bb58-be7b3dda08a1Barata<p>Probably because in differential mode the result is signed.</p> <p>But that doesn&#39;t explain why some people are reporting negative values in Single Ended mode due to miss calibration. I don&#39;t know what this means.</p><div style="clear:both;"></div>