https://devzone.nordicsemi.com/f/nordic-q-a/3709/nrf51822-sd_nvic_enableirq-gpiote_irqn--hardfault_handlerThank you for your reply,Nikita description of my system: Hardware:nrf51822,pca10001 Software:sdk5.20,run the softdevice s120 I call these functions sd_nvic_SetPriority()/sd_nvic_EnableIRQ() is for use GPIOTE interrupt ,if i push a button ,it shoulden-USTelligent Community 13Wed, 03 Sep 2014 05:59:25 GMThttps://devzone.nordicsemi.com/thread/13460?ContentTypeID=1Wed, 03 Sep 2014 05:59:25 GMT137ad170-7792-4731-bb38-c0d22fbe4515:b58afc97-2a97-4291-a894-e115aff67c0eNikita<p>It seems you are calling sd_nvic_SetPriority()/sd_nvic_EnableIRQ() before you enable softdevice in your program. If you need to init gpiote before softdevice you can just use nvic_EnableIRQ.</p><div style="clear:both;"></div>