https://devzone.nordicsemi.com/f/nordic-q-a/57476/nrf52-with-mpu9255-power-saveHi, I am using the example nrf5-ble-mpu-simple from nrf5-mpu-examples-master to do the following: a) send a BLE beacon advertisement (non connectable) b) periodically sample the accelerometer readings from the connected MPU9255 c) change the advertisementen-USTelligent Community 13Wed, 12 Feb 2020 11:29:19 GMThttps://devzone.nordicsemi.com/thread/233938?ContentTypeID=1Wed, 12 Feb 2020 11:29:19 GMT137ad170-7792-4731-bb38-c0d22fbe4515:5cd1c78d-6358-4895-a68e-db7aa4d9ae17Jared<p>Hi,</p> <p>I&#39;m not sure how the accelerometer will react when the nRF is configured to sleep in SYSTEM OFF ( you would have to test and see) but there are several ways to wake up the nRF from&nbsp; SYSTEM OFF sleep as described <a href="https://infocenter.nordicsemi.com/topic/ps_nrf52833/power.html?cp=4_1_0_4_2_2#unique_751457334">here</a>. Note that waking up from SYSTEM OFF will reset the application. If you don&#39;t want to reset the application upon wake-up, then you could try using SYSTEM ON sleep instead by calling a&nbsp; __WFE. This will keep the nRF in IDLE mode while it waits for an event, the tradeoff is the higher current consumption versus using SYSTEM OFF.</p><div style="clear:both;"></div>