https://devzone.nordicsemi.com/f/nordic-q-a/76152/nrf5340-vdd-1-8vHi, I have some of peripherals at 1.8V and some at 3.3V that I&#39;d like to run off the nRF5340. Is there a way to selectively set which interface is in a specific voltage domain? I think I can connect VDD to 1.8V which would make the GPIO voltage domainen-USTelligent Community 13Wed, 09 Jun 2021 15:53:52 GMThttps://devzone.nordicsemi.com/thread/314539?ContentTypeID=1Wed, 09 Jun 2021 15:53:52 GMT137ad170-7792-4731-bb38-c0d22fbe4515:84a9b7e2-df9f-4723-a165-73b82b3487ffahrnicek<p>Okay. I thought it was worth asking. Thank you.</p> <p>Andy</p><div style="clear:both;"></div>https://devzone.nordicsemi.com/thread/314538?ContentTypeID=1Wed, 09 Jun 2021 15:45:32 GMT137ad170-7792-4731-bb38-c0d22fbe4515:76337470-4823-49f1-bc26-eb4000dac06aahrnicek<p>Okay. I thought it was worth asking. Thank you.</p> <p>Andy</p><div style="clear:both;"></div>https://devzone.nordicsemi.com/thread/314445?ContentTypeID=1Wed, 09 Jun 2021 11:47:51 GMT137ad170-7792-4731-bb38-c0d22fbe4515:26df30cf-822e-412d-9548-d85537c6e31cKenneth<p>I don&#39;t see any other way than having some level shifters really. All GPIO&#39;s run on the same power domain, and if you feed voltage higher than VDD+0.3V (=2.1V in your case) on a GPIO you will trigger the internal ESD diodes, which will likely cause the GPIOs to experience EOS damage over time.</p> <p>Kenneth</p><div style="clear:both;"></div>