https://devzone.nordicsemi.com/f/nordic-q-a/78902/gpio-wakeup-from-systemoffHi Team, SDK used 17.0.2 I am able to successfully wakeup the device from systemOFF using a gpio (not from sensor). In this case it is consuming only 350 nA (300 = nRF + 50 = Sensor), as expected. In this case a sensor is also running (HDC2080) .en-USTelligent Community 13Mon, 13 Sep 2021 21:59:33 GMThttps://devzone.nordicsemi.com/thread/329287?ContentTypeID=1Mon, 13 Sep 2021 21:59:33 GMT137ad170-7792-4731-bb38-c0d22fbe4515:888607e2-e4f5-4b26-a902-7b3c73d1a0d4kizhimon<p>this was hardware issue</p><div style="clear:both;"></div>https://devzone.nordicsemi.com/thread/326509?ContentTypeID=1Wed, 25 Aug 2021 11:00:22 GMT137ad170-7792-4731-bb38-c0d22fbe4515:2e18a448-fbd6-4d2c-92a6-d923335f4794Kenneth<p>This was a bit odd yes.</p> <p>Any difference if sensor is not physically connected? Any difference if only pin14 have sense enabled (without pin 13)? Do you have any analog measurement (e.g. oscilloscope) on the two pins in question? Does the current consumption &quot;scale&quot; if you adjust VDD?</p> <p>Kenneth</p><div style="clear:both;"></div>