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Which clock is used for timing after BLE establishes a connection?

Hi,
I am analyzing the issue that the BLE module can maintain a relatively short connection distance. Besides the transmission power and frequency offset, I also take into account the factor of the clock, because the connection is a synchronous event and must have a certain relationship with the clock. 
I would like to ask, in the connection event, what type of clock is used to determine the next connection time? Is it a hardware TIMER or a software RTC? In other words, is it related to a high-frequency clock or a low-frequency clock?
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