Required signals to perform DFU over UART

I'm designing the schematic of a board with a nRF52832 module. I would like to be able to perform a Device Firmware Update through UART, using for example the nRF Util or SDI. The nRF52 DK hardware demo board, which I use as a reference, shows that 4 pins, RTS, TXD, CTS, RXD, are used to connect a usb-enabled microcontroller to the nRF52832.

Are RTS and CTS pins required to perform DFU over UART in a nRF52832 module? Or are just TXD and RXD enough?

Related