Problem with UART TX or RX lines

I have a question regarding an issue we observed in some of our products. In a few units from our large production batch, we are experiencing problems with the UART TX or RX lines on the NRF52833.

Specifically:

  • In some units, the NRF52833 does not respond to commands, preventing data transmission via UART, although we still receive data logs, so TX line doesn't work but RX works
  • In other units, we can send data via UART, but we cannot receive any data. For example, we can send a reboot command, and the MCU reboots successfully, so TX works, but RX doesn't

This issue does not seem to be related to our PCB design, as the UART is connected to a pin header and we use an external FTDI for communication. Additionally, we resoldered a new NRF52833 onto a PCB with a non-working UART, and the UART started working.

My question is:

  • Is it possible that the UART on the NRF52833 is being damaged during the production process, such as during soldering, while other functionalities remain unaffected?
  • Could ESD selectively destroy only the UART peripheral?

This issue has been observed in only a few units (for example on four out of a production batch of 1000).

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