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APK can't write a data to 51822

Hi, I flashed the Proximity Application to nrd51822,with s110_nrf51822_6.0.0-5.beta. the chip run right, and I used the NRF Master Control Panel, when I write data 0X02 to immediate Alert service,the led is on. when I used my own apk, and write 0x02 to the service, 51822 can't receiced the data,the led is not on; but when I used the Master Control panel write data to 51822 first, then close the Mater control Panel , then open my apk, this time my apk can write data to 51822,the led is on; why, I can't write data to 51822 standalone first ? when I use NRF Master Control panel, write data to 51822, dose it do some authentication between my phone and 51822?

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