I developed a custom application on the 52840DK and have now moved this over to a custom PCB of my own design. I can compile OK and can start a debug session from "main" but part way through the code, I get a fatal "Kernel Panic" error. I was able to track it down to a interrupt from Timer 0 which I understand is used by the MPSL system. The interrupt takes the program counter to a function in "mpsl_init.c" :