Is 4-layer PCB always better than 2-layer ?

Question

I had a design on 4-layer PCB with nrf51822, then the requirement was changed, then the 2-layer is sufficient for routing. 
 But I thought 4-layer PCB is better for RF circuit, so I can remain 4-layer PCB with a Ground plane and Power plane. 
 Is my thought true ? Or I can just use a 2-layer then ?

James Yu · Accepted Answer

As long as you follow the PCB guidelines in the product specifications it should be fine. 
 A PCB with a minimum of two layers, including a ground plane, is recommended for optimal performance.
On PCBs with more than two layers, put a keep-out area on the inner layers directly below the antenna
matching circuitry (components between device pins ANT1, ANT2, VDD_PA, and the antenna) to reduce the
stray capacitances that influence RF performance. 
 
 So a 2 layer board will be sufficient if you have a pretty solid ground plane with little breaks, otherwise it may be better to go with 4 layers.

Is 4-layer PCB always better than 2-layer ?

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