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Sending PDF files through BLE_APP_UART

Hi,

I am using ble_app_uart service in my application. I am trying to send files using teraterm tool. If I am sending .txt or .doc files there is no disconnection in the devices. But if I am sending PDF or PPT file there is a disconnection between central and peripheral device. Is there any issue in sending PDF files? Also I am seeing some data loss while sending .txt or  .doc files.

Need a urgent solution for this.