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Can't run BLE examples with PPK attached

I'm in the process of evaluating the BLE functionality via the 52840 dev kit. I ran a number of examples without issue and just recently received power profiler kits so I could monitor power usage. I followed the setup and cut SB40 on the board and attached the kit. I was able to run the Power Profiler app and everything is recognized and producing output. The problem is now I can't seem to program the dev kits with the power profiler attached. Whenever I attempt to run one of the SDK examples in Segger, it builds and deploys but when I try to debug it immediately breaks with a "stopped by vector catch" and not much other information. 

By removing the PPK and placing a jumper on P22 I'm able to run examples again.

Secondary issue: I have 2 DK and PPK pairs, with one set I am able to run the nRF Connect BLE app fine with the PPK attached, but with the other one the entire app turns white and I can't do anything after connecting.

Setup:

nRF52840-DK dev kit

Power Profiler Kit, all switches set to "DK"

USB to desktop computer

Windows 10

SDK 15.3

Segger 4.16

nRF Connect v3.0.0

Bluettooth Low Energy app v2.3.0

Power Profiler app v2.2.0

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