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BLE working mode configuration

I have a peripheral and central units, both based on nRF52832.

Both of them have to be able to initiate a messege to the other at any time.

Both of them have be able to listen to a messege from the other at any time.

In order to get the most power savings, would it be better to leave a BLE connection at all times between the two? or move back to advertise stage (every say 300msec interval)?

Regards,

Gil

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