Can a slave device send data without receiving an empty packet from the master device in a connection event?

[Subhanshu Sahu]

I have read that at each connection event master will send the first packet (empty payload).

In a case where slave latency > 1, the slave will not be listening to master for that many connection events that means will not be receiving the empty packet sent by the master at each new connection event, so in this case, can slave send data.