Hello!
In our design we need BLE 5 solution with maximum allowable by reulation +20 dBm TX power. It is not a problem to use a separate PA for achieving that power, however, according to ETSI and our duty cycle, Adaptive Frequency Hopping is a must when power exceeds 10dBm. At the moment we are in feasibility stage, where we evaluate possible solutions from many manufacturers. As far as I understand nRF52 soft device does not support AFH, however Silicon Labs solution does. The question is are you planning to implement AFH function and, if yes, when? If not, it can be that you will miss some potential clients because of that