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nRF52840, can any Pin be configured for I2C & SPI?

Hi, 

we are moving from nRF52840 DK to integrate nRF52840 to our solution. In the datasheet for pin assignments (Link) it states "recommendation usage; Standard drive, low frequency I/O only"

Does that mean that this Pin is not recommended to be configured for high frequency implementation such as SPI or I2C?
What is considered Low Frequency, 50Hz?

It is actually just based on one question, can any pin be configured as I2C or SPI? 


Best Regards,
Hamza 

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