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nrf9160 VDD_GPIO

My use case is that the nrf9160 is running as a serial lte modem and I have a host controller that is controlling the ENABLE pin.  VDD will always be powered so can I leave VDD_GPIO always powered as well?  Or does VDD_GPIO need to be switched off when ENABLE=0?  I'm wondering if this is the typical way to handle this use case.  Thank you

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