nRF5340 Port Pins 5 Volt Compatibility

Dear, I want to interface nRF5340 to normal 16x2 Alphanumeric LCD running on 5 Volt. Are the Port pins of nRF5340  5 Volt compatible when nRF is running with 3.3 Volt supply ? I am using nRF5340DK kit and SES IDE with nRF Connect SDK. Please guide in that refference. May, we run nRF5340DK SOC on 5 Volt ?