NRF9160-DK - Doesn't power after external supply

Hello,

I tried to power the nrf9160-DK with external supply on port P21, as suggered : 

https://infocenter.nordicsemi.com/pdf/nRF9160_DK_HW_User_Guide_v1.0.pdf

So I put a li-ion cell directly (which was charged at 4.1V) to try the asset_tracker outside.

But after 5 minutes it continuously blink LED 1 and 4.

So I unplugged the power, go back to the desk and connect the USB cable to see what's going on, and surprise, the LED 5 turns on for 1s, then go back to off.

I see the U24 heats a lot when the LED5 is ON.

If I disconnect the nRF current measurement jumper P22, the board works but I can't access to the NRF (of course), as soon as I reconnect P22, the board turns off.

I'm pretty sure I didn't do any short-circuit or reverse polarity or put more than 5V on external supply, but now I can't make the board works again.

Now, when I use external supply, I have the same result.

Do you know how I can fix that?

Thank you

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