There is already a case on github:
https://github.com/zephyrproject-rtos/zephyr/issues/44586
But essentially we see an issue with nrf5340, where we get random crashes and hangs when sending IPC messages from netcore to appcore. I have created a pretty barebone application which is linked to in the github issue that recreates the issue. I have ordered some nrf5340dk kits, but have not received them yet, but it should be pretty straight forward to port this application to nrf5340dk. The issue seems also very hardware dependent, and currently we only got two devices where the issue happens often, but it happens on all of our devices.
The application is sending a message from the netcore to the application core every second which then logs it using the logging infrastructure. The logging backbone is UART. What we see is that the application either hangs (most common) or reboots both with and without core dumps.