Hi there,
We are designing a coin cell (3 V nominal) battery powered product; we'd like the ability to run it all the way down to 2.0 V for maximum lifetime. To get the most out of the battery, the preference is to run in Normal Voltage mode (1.7 V <= VDD <= 3.6 V) instead of High Voltage Mode (2.5 V <= VDD <= 5.5 V)
Part of the design requires a 1.8 V reference voltage (nothing particularly onerous in terms of accuracy, ripple etc.). It need only be a couple of hundred microamps, so a setting the GPIO voltage to 1.8 V and flipping a pin high is a fit-for-purpose approach.
Looking at the nRF52833 PS, it states
In Normal Voltage mode, the GPIO high level equals the voltage supplied to the VDD pin. In High Voltage mode, it equals the level specified in register REGOUT0.