Custom board working like a nrf52840 dongle

I have a custom board with a BMD-345-A-R module and working with the nrf connect sdk 2.2.0

I have builded and flashed the openthread/cli sample for my nrf52840DK and its working perfectly but if I change the board to "nrf52840dongle" in the build configuration it doesnt work in my custoom board. I change to nrf52840dongle because if I have installed the dongle bootloader I can upload every app from sdk 17.0 with 10059 label to my custom board and it works.

I have been checking the .dts and my layout:

My final purpose is install MCUBoot within my custom board but my first step is running openthread/cli example without bootloaders nor MBRs nor softdevices.

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