nRF5340 DK and PPK2 not working

Question

Hi, 
 I am using the PPK2 to evaluate the nRF5340. Neither of these devices is currently working properly, I think the underlying cause has something to do with USB that's why I created only one issue. 
 
 PPK2 
 
 It works the first time after restarting my computer. If I then close Power Profiler and select the device again it hangs at ' Opening device with s/n EAA9B4F32C15 '. After that it will not be usable. I have tried unplugging/replugging the USB, using with a powered USB hub, without a USB hub, nothing works except restarting my PC. It's identical to this issue but it never got a solution unfortunately: https://devzone.nordicsemi.com/f/nordic-q-a/76900/cant-open-power-profiler-kit-2-on-windows-pc 
 
 nRF5340 DK 
 
 It can connect fine. When I press the 'read' button to read the memory I get:

15:04:19.393 Failed to get device memory map: async task failure for id: 1865463227 msg: JLINKARM_DLL_TIME_OUT_ERROR (Origin: "Error when running fw program.")
15:04:19.393 Error when reading device

I tried the same with nrfjprog command line utility and it gave the same result. I have attached the log here for reference:

Furthermore I have tried: 
 
 Using a personal laptop. Both devices work fine on this machine, no issues whatsoever. This makes me sure that it's something with my installation. 
 Reinstalling. I just did a clean install of all software involved, including windows drivers. Unfortunately it made no difference.

Alec Werning · Answer

It works the first time after restarting my computer. If I then close Power Profiler and select the device again it hangs at ' Opening device with s/n EAA9B4F32C15 '. After that it will not be usable. I have tried unplugging/replugging the USB, using with a powered USB hub, without a USB hub, nothing works except restarting my PC. It's identical to this issue but it never got a solution unfortunately: https://devzone.nordicsemi.com/f/nordic-q-a/76900/cant-open-power-profiler-kit-2-on-windows-pc 
 
 I ran into this same issue after moving from one Windows PC to a different Windows PC (same manufacturer, different model). I noticed the new, problematic PC does not have all of the same Nordic Semiconductor drivers installed as the old, working PC. Nordic Drivers on Problematic PC (with nRF Connect installed) 
 
 Windows Driver Package - Nordic Semiconductor ASA (usbser) Ports (05/11/2018 1.0.1.0) 
 Windows Driver Package - Nordic Semiconductor ASA (WinUSB) Nordic Semiconductor DFU (08/21/2020 1.0.0.1)

Nordic Drivers on Working PC (with nRF Connect and nRFgo Studio) 
 
 Windows Driver Package - Nordic Semiconductor ASA (usbser) Ports (05/11/2018 1.0.1.0) 
 Windows Driver Package - Nordic Semiconductor ASA (WinUSB) Nordic Semiconductor DFU (08/21/2020 1.0.0.1) 
 Windows Driver Package - Nordic Semiconductor CDM Driver Package - Bus/D2XX Driver (01/18/2013 2.08.28) 
 Windows Driver Package - Nordic Semiconductor CDM Driver Package - VCP Driver (01/18/2013 2.08.28) 
 Windows Driver Package - NORDICSEMI CDM Driver Package (01/28/2013 2.08.15)

The only difference in setup is that nRFgo Studio was installed on the old PC. Installing nRFgo Studio on the new PC resolved the hung connecting process and allowed the PC to work properly with the power profiler.