Programs never make it to main()

I've designed a custom board with the Laird BL5340 module and even the Blinky sample fails to run properly. I get the following debug output no matter what I try:

I've got UART1, I2S (master), and LED6, 7, and 8 connected using the same pins as the NRF5340 Audio DK. The module is powered from 3.3V (both VDD and VDD_HV) and reset is pulled up with a 4.7K resistor. Other than JTAG nothing else is connected and remaining port pins are floating.

I get the same behavior when configured for my custom board or for the nrf5340_audio_dk_nrf5340_cpuapp. I'm using version 2.2.0 of the SDK with a Segger j-link debugger. I've been able to program and run programs, including the BLE Audio samples on the DK. I can also use the j-link with DK, so I don't think it's my basic setup.

Any suggestions would be appreciated!

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