Switch to power off nrf52840

Hi!

I'm designing a wireless PC peripheral with NRF52840. VDDH is connected to +3V3 from BMS, and VBUS is connected to USB voltage.

Is it necessary to connect VBUS to USB+5V to detect USB?

When I have the device connected to USB and I want to power off the device, do I need to disconnect VDDH only or VBUS too?

Can I put a switch directly or this is dangerous due to the transients and I have to use mosfets?

Thanks regard.

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