Fail to run the example code in pc-ble-driver

Hi, I was currently trying to run the example code on my linux virtual machine(virtual box).

I followed the steps from https://github.com/NordicSemiconductor/pc-ble-driver/tree/master

and the results shows that  Serial port used: /dev/ttyACM0

                                             Baud rate used: 1000000
                                            Info: Successfully opened /dev/ttyACM0. Baud rate: 1000000. Flow control: none. Parity: none.
                                            Status: 6, message: Target Reset performed
                                             Status: 0, message: No response from device. Tried to send packet 6 times.
                                             Failed to open nRF BLE Driver. Error code: 0x0D
I have tried all the connectivity files and all of them do not work. Can anyone please help me on this? Thanks!!
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