Is there any relation between connection parameters and occasionally disconnection

[Sansei]

I have a system, with cc2540 as central and n51822 as peripheral with s130. Sometimes while they are close to each other, the connection link gets lost. I disabled updating the connection parameters on the client(cc2540), and I set them just on peripheral. Is it acceptable or not? Where I can find best practices/settings on these parameters while I need to get fast feedback on getting out from the RSSI range and also need to do as much as fast on reconnecting;

Could you please clarify me with the impression of these parameters on my occasional disconnection problem?

[Petter Myhre]

It is the central device that dictates the connection parameters (when connection is established), it can then choose to do a connection parameter update to change them.

What are your actual connection parameters? See this for how to check. What are the connection parameters when you get the BLE_GAP_EVT_CONNECTED event? Do you get any BLE_GAP_EVT_CONN_PARAM_UPDATE events? What are the connection parameters then?